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Zhongmei He Selected Research

palmatine

4/2024Palmatine improves cognitive dysfunction in Alzheimer's disease model rats through autophagy pathway and regulation of gut microbiota.
12/2023Palmatine Protects PC12 Cells and Mice from Aβ25-35-Induced Oxidative Stress and Neuroinflammation via the Nrf2/HO-1 Pathway.
10/2023Palmatine attenuates LPS-induced neuroinflammation through the PI3K/Akt/NF-κB pathway.
11/2022Network pharmacology and molecular docking integrated strategy to investigate the pharmacological mechanism of palmatine in Alzheimer's disease.

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Zhongmei He Research Topics

Disease

8Alzheimer Disease (Alzheimer's Disease)
04/2024 - 09/2018
7Neoplasms (Cancer)
01/2024 - 05/2014
4Inflammation (Inflammations)
12/2023 - 01/2022
3Neuroinflammatory Diseases
03/2024 - 10/2023
2Cognitive Dysfunction
04/2024 - 05/2023
2Ulcerative Colitis
01/2024 - 01/2023
2Reperfusion Injury
12/2023 - 08/2023
2Brain Ischemia (Cerebral Ischemia)
12/2023 - 08/2023
2Brain Injuries (Brain Injury)
05/2023 - 11/2022
2Breast Neoplasms (Breast Cancer)
01/2020 - 05/2014
2Neoplasm Metastasis (Metastasis)
01/2020 - 05/2014
1Acute Kidney Injury (Acute Renal Failure)
05/2024
1Mitochondrial Diseases (Mitochondrial Disease)
03/2024
1Amenorrhea
01/2024
1Uterine Hemorrhage (Uterine Bleeding)
01/2024
1Vaginal Discharge
01/2024
1Osteoporosis
12/2023
1Oligospermia (Oligozoospermia)
12/2023
1Pheochromocytoma
12/2023
1Pain (Aches)
12/2023
1Cardiac Arrhythmias (Arrythmia)
12/2023
1Eclampsia
12/2023
1Hemorrhage
12/2023
1Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)
12/2023
1Liver Diseases (Liver Disease)
11/2023
1Ischemia
08/2023
1Diarrhea
08/2023
1Nasal Obstruction
01/2022
1Hepatocellular Carcinoma (Hepatoma)
01/2022
1Edema (Dropsy)
01/2022
1Cough
01/2022
1Pruritus (Itching)
01/2022
1Sneezing
01/2022
1Rhinorrhea
01/2022
1Allergic Rhinitis
01/2022
1Pituitary Neoplasms (Pituitary Adenoma)
01/2020
1Cardiovascular Diseases (Cardiovascular Disease)
01/2020
1Necrosis
09/2018
1Body Weight (Weight, Body)
06/2018

Drug/Important Bio-Agent (IBA)

5AntioxidantsIBA
01/2024 - 09/2018
5Proteins (Proteins, Gene)FDA Link
12/2023 - 09/2018
4palmatineIBA
04/2024 - 11/2022
3FlavonoidsIBA
12/2023 - 01/2023
2CytokinesIBA
05/2024 - 01/2022
2Therapeutic UsesIBA
01/2024 - 12/2023
2GinsenosidesIBA
12/2023 - 08/2020
2SaponinsIBA
11/2023 - 05/2014
2Peptides (Polypeptides)IBA
08/2023 - 05/2011
2Interleukin-6 (Interleukin 6)IBA
11/2022 - 01/2022
2AutoantibodiesIBA
01/2015 - 05/2011
1Leucine (L-Leucine)FDA Link
05/2024
1NucleotidesIBA
05/2024
1Antidepressive Agents (Antidepressants)IBA
03/2024
1InflammasomesIBA
03/2024
1GlycosidesIBA
03/2024
1Fluoxetine (Prozac)FDA LinkGeneric
03/2024
1LigandsIBA
12/2023
1Adenosine Triphosphate (ATP)IBA
12/2023
1Neuroprotective AgentsIBA
12/2023
1Amyloid beta-PeptidesIBA
12/2023
1Cholinesterase Inhibitors (Anticholinesterases)IBA
12/2023
1Dopamine (Intropin)FDA LinkGeneric
12/2023
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
12/2023
1Cholinergic Antagonists (Anticholinergics)IBA
12/2023
1baicalinIBA
11/2023
1Anti-Bacterial Agents (Antibiotics)IBA
08/2023
1ginsenoside Rg1IBA
05/2023
1dihydromyricetinIBA
05/2023
1aurantiamideIBA
01/2023
1Dextran SulfateIBA
01/2023
1Reactive Oxygen Species (Oxygen Radicals)IBA
11/2022
1Bisbenzimidazole (Hoechst 33258)IBA
11/2022
1SincalideFDA Link
11/2022
1FITC-annexin A5IBA
11/2022
1LipopolysaccharidesIBA
11/2022
1InterleukinsIBA
11/2022
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2022
1Immunoglobulin E (IgE)IBA
01/2022
1compound 21IBA
01/2022
1Anti-Allergic Agents (Antiallergic Agents)IBA
01/2022
1Interleukin-5 (Interleukin 5)IBA
01/2022
1Histidine (L-Histidine)FDA Link
10/2020
1Amyloid (Amyloid Fibrils)IBA
08/2020
1Simvastatin (Zocor)FDA LinkGeneric
01/2020
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2020
1CholesterolIBA
01/2020
13-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA
01/2020
1Oxidoreductases (Dehydrogenase)IBA
01/2020
1Small Interfering RNA (siRNA)IBA
01/2020
1EnzymesIBA
09/2018
1Galactose (Galactopyranose)FDA LinkGeneric
09/2018
1ImmunosorbentsIBA
09/2018
1Aluminum ChlorideIBA
09/2018
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
09/2018
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
09/2018
1Soybean OilFDA LinkGeneric
06/2018
1SolutionsIBA
06/2018
1Caffeine (No Doz)FDA LinkGeneric
10/2016

Therapy/Procedure

2Therapeutics
08/2023 - 05/2014
1Aftercare (After-Treatment)
12/2023